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Advisory Cannabidiol (CBD)—Potential Harms, Side Effects, and Unknowns

Substance Abuse and Mental Health Services Administration, 2023

This advisory introduces readers to cannabidiol (CBD), how it is derived, and how it differs from delta-9 THC and other cannabinoids. The advisory focuses on the risks and harms of CBD, especially those sold over the counter. This advisory also clarifies common misconceptions about CBD, given its broad availability and marketing for several medical conditions despite limited evidence of efficacy.

It is critical that the general public be made aware of the potential harms associated with CBD use, and parents, in particular, should be advised to not let their children use non-FDA-approved CBD products.

View Document (PDF 1.9 MB)

Topic(s): Cannabis

Section: Policy and Practice Resources

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To locate general treatment services, visit the Substance Abuse and Mental Health Services Administration’s (SAMHSA’s) Treatment Locator online or call 1-800-662-4357 (HELP). This service provides referrals to local treatment facilities, support groups, and community-based organizations. It is a free, confidential, 24-hour-a-day, 365-day-a year information service, in English and Spanish, for individuals and family members needing treatment for a mental and/or substance use disorder.

To locate general treatment services, visit the Substance Abuse and Mental Health Services Administration’s (SAMHSA’s) Treatment Locator online or call 1-800-662-4357 (HELP). This service provides referrals to local treatment facilities, support groups, and community-based organizations. It is a free, confidential, 24-hour-a-day, 365-day-a year information service, in English and Spanish, for individuals and family members needing treatment for a mental and/or substance use disorder.

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If you suspect a child has been harmed by abuse or neglect, please call 1-800-422-4453.

If you suspect that a child has been harmed or is at risk of being harmed by abuse or neglect, call the National Child Abuse Hotline at Call the National Child Abuse Hotline at 1-800-422-4453. Serving the United States and Canada, the hotline is staffed 24 hours a day, 7 days a week with professional crisis counselors who—through interpreters—provide assistance in over 170 languages. All calls, texts, and chats are confidential. If you believe a child is in immediate danger of harm, call 911 first.

If you suspect that a child has been harmed or is at risk of being harmed by abuse or neglect, call the National Child Abuse Hotline at 1-800-422-4453. Serving the United States and Canada, the hotline is staffed 24 hours a day, 7 days a week with professional crisis counselors who—through interpreters—provide assistance in over 170 languages. All calls, texts, and chats are confidential. If you believe a child is in immediate danger of harm, call 911 first.

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For free and confidential support for people in distress, 24/7, please call or text 988, chat 988Lifeline.org, or call 1-800-273-8255.

If you or someone you know is having thoughts of suicide or experiencing a mental health or substance use crisis, help is available and there are options to receive compassionate care. You can call or text 988 or chat 988Lifeline.org. You can also call the National Suicide Prevention Lifeline at 1-800-273-TALK (1-800-273-8255). Both are confidential and available 24/7 to everyone in the United States and will connect you to a trained counselor at a suicide crisis center nearest you.

If you or someone you know are in crisis, thinking about harming yourself, attempting suicide, or harming another person, tell someone who can help right away. There are options to help you cope. Call the toll-free, 24-hour hotline of the National Suicide Prevention Lifeline at 1-800-273-TALK (1-800-273-8255) to be connected to a trained counselor at a suicide crisis center nearest you. The National Suicide Prevention Lifeline is confidential support, available 24/7 to everyone in the United States.

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Administration for Children & FamiliesSubstance Abuse and Mental Health Services Administration
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An official website of the Administration for Children and Families and the Substance Abuse and Mental Health Services Administration

National Center on Substance Abuse and Child Welfare